How the treatment of breast cancer has evolved in last 15 years

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5/24/20232 min read

How the treatment of breast cancer has evolved in last 15 years
How the treatment of breast cancer has evolved in last 15 years

Evolution of Breast Cancer Treatment Over the Last 15 Years.

Abstract: Breast cancer is a complex and heterogeneous disease affecting millions of women worldwide. Over the past 15 years, significant advancements have been made in understanding the molecular basis of breast cancer, leading to the development of more personalized and targeted treatment approaches. This article provides an overview of the evolution of breast cancer treatment over the last 15 years, highlighting key breakthroughs in surgery, radiation therapy, systemic therapy, and supportive care. The advancements discussed herein have led to improved outcomes, reduced treatment-related toxicity, and enhanced quality of life for breast cancer patients.

  1. Introduction Breast cancer is one of the most prevalent cancers among women globally, and its treatment landscape has undergone significant transformations over the past 15 years. This article aims to summarize the key developments in breast cancer treatment, highlighting advancements in surgery, radiation therapy, systemic therapy, and supportive care.

  2. Surgery:

    2.1. Breast-Conserving Surgery (BCS)

    2.2. Mastectomy Techniques

    2.3. Sentinel Lymph Node Biopsy

    2.4. Axillary Lymph Node Dissection

    2.5. Oncoplastic Surgery.

  3. Radiation Therapy

    3.1. External Beam Radiation Therapy (EBRT)

    3.2. Accelerated Partial Breast Irradiation (APBI)

    3.3. Hypofractionated Radiation Therapy

    3.4. Intraoperative Radiation Therapy (IORT)

    3.5. Proton Therapy.

  4. Systemic Therapy

    4.1. Adjuvant Chemotherapy

    4.2. Neoadjuvant Chemotherapy

    4.3. Hormone Therapy

    4.4. Targeted Therapy

    4.5. Immunotherapy.

  5. Personalized Medicine and Biomarkers

    5.1. HER2-Positive Breast Cancer

    5.2. Hormone Receptor-Positive Breast Cancer

    5.3. Triple-Negative Breast Cancer

    5.4. Liquid Biopsies.

  6. Supportive Care

    6.1. Antiemetic Therapy

    6.2. Targeted Therapies for Side Effect Management

    6.3. Palliative Care and Symptom Management.

  7. Survivorship and Quality of Life

    7.1. Survivorship Care Plans

    7.2. Psychological Support and Counseling

    7.3. Physical Rehabilitation and Exercise Programs.

  8. Clinical Trials and Future Directions

    8.1. Precision Medicine and Genomic Profiling

    8.2. Immunotherapeutic Approaches

    8.3. Novel Drug Delivery Systems

    8.4. Circulating Tumor DNA (ctDNA) Monitoring.

  9. Conclusion Breast cancer treatment has witnessed significant advancements over the past 15 years, with a shift towards more personalized and targeted approaches. These developments in surgery, radiation therapy, systemic therapy, and supportive care have led to improved outcomes, enhanced patient experiences, and a better quality of life for individuals affected by breast cancer. Continued research and clinical trials hold the promise of further revolutionizing breast cancer treatment in the future.